Moveover,Montgomery's account suggests that there are universally agreed medical ethical principles, whereas such principles differ both across and within jurisdictions, and also evolve time. Religious and cultural perspectives have important practical effects on biomedical principles. So, for example, a concept such as the sanctity of life is commonly respected by different faith groups, and is inherent in legal frameworks across jurisdictions. But sanctity of life can mean very different things when applied in practice. Its application is predicted upon agreement as to what life means and when it begins and ends.In addition, while the principles may be agreed in general, the extent to which it is amenable to exceptions may vary considerably.